A new and efficient high-performance electrochemical glucose sensor based on a metallopolymer derived from a cobaltate (III) Schiff base complex

Darío M. González, Loreto A. Hernández, Jocelyn Oyarce, Andrea Alfaro, Néstor Novoa, Jonathan Cisterna, Iván Brito, David Carrillo, CECILIA CAROLINA MANZUR NAZAL

Research output: Contribution to journalArticlepeer-review

Abstract

Through a simple and effective reaction of the cobalt (II) acetate tetrahydrate with a new ONO-tridentate Schiff base ligand (L1), which contains a thiophenyl group, a mono-anionic complex of formula: [{4-Th-C6H4-C(O)CH-C(CH3)=N-C6H4-2-O}2Co]-[Bu4N]+ (C1) was isolated. Spectroscopic tools (1H and 13C NMR, FT-IR) and the crystal structure revealed that C1 consists of a mononuclear six-coordinate anionic Co(III) center with a pseudo-octahedral geometry, and one tetrabutylammonium counterion to satisfy the negative charge of the coordination entity [CoIII(L1)2]-. Electropolymerization of C1 produces a conductive metallopolymer deposit on fluorine-doped tin oxide (FTO) electrodes, which acts as an efficient glucose sensor, showing a linear amperometric response for glucose within a concentration range of 1.97 × 10 −7 M to 3.88 × 10−6 M (R2 = 0.993), limit of detection (LOD) of 9.27 × 10−7 M and limit of quantification (LOQ) of 9.24 × 10−6 M. This electrochemical sensor, which exhibit excellent reproducibility in the manufacturing process, was stable in environmental conditions and showed good reproducibility of the measurements for two weeks. In addition, the metallopolymer deposit was characterized by electrochemical techniques (cyclic voltammetry) and SEM microscopy.

Original languageEnglish
Article number116633
JournalSynthetic Metals
Volume271
DOIs
StatePublished - Jan 2021
Externally publishedYes

Keywords

  • Electrodeposition
  • Glucose sensor
  • Metallopolymer
  • Schiff base cobaltate (III) complex

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