TY - JOUR
T1 - A new and efficient high-performance electrochemical glucose sensor based on a metallopolymer derived from a cobaltate (III) Schiff base complex
AU - González, Darío M.
AU - Hernández, Loreto A.
AU - Oyarce, Jocelyn
AU - Alfaro, Andrea
AU - Novoa, Néstor
AU - Cisterna, Jonathan
AU - Brito, Iván
AU - Carrillo, David
AU - MANZUR NAZAL, CECILIA CAROLINA
N1 - Funding Information:
This research was conducted as part of the Chilean-French International Associated Laboratory for “Multifunctional Molecules and Materials” (IRP M3-CNRS N° 1207). We gratefully acknowledge financial support from FONDECYT (Chile) , grants number 1140903 and 1190034 (C.M. and D.C.); FONDEQUIP (Chile) , grant EQM130154 (C.M. and D.C.), EQM130021 and EQM180024 (I.B. and J.C.); the Vice-Rectoría de Investigación y Estudios Avanzados , Pontificia Universidad Católica de Valparaíso , Chile (D.G., C.M. and D.C.). J.O. thanks CONICYT (Chile) for her graduate fellowship N° 21171363.
Funding Information:
This research was conducted as part of the Chilean-French International Associated Laboratory for ?Multifunctional Molecules and Materials? (IRP M3-CNRS N? 1207). We gratefully acknowledge financial support from FONDECYT (Chile), grants number 1140903 and 1190034 (C.M. and D.C.); FONDEQUIP (Chile), grant EQM130154 (C.M. and D.C.), EQM130021 and EQM180024 (I.B. and J.C.); the Vice-Rector?a de Investigaci?n y Estudios Avanzados, Pontificia Universidad Cat?lica de Valpara?so, Chile (D.G. C.M. and D.C.). J.O. thanks CONICYT (Chile) for her graduate fellowship N? 21171363.
Publisher Copyright:
© 2020 Elsevier B.V.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/1
Y1 - 2021/1
N2 - Through a simple and effective reaction of the cobalt (II) acetate tetrahydrate with a new ONO-tridentate Schiff base ligand (L1), which contains a thiophenyl group, a mono-anionic complex of formula: [{4-Th-C6H4-C(O)CH-C(CH3)=N-C6H4-2-O}2Co]-[Bu4N]+ (C1) was isolated. Spectroscopic tools (1H and 13C NMR, FT-IR) and the crystal structure revealed that C1 consists of a mononuclear six-coordinate anionic Co(III) center with a pseudo-octahedral geometry, and one tetrabutylammonium counterion to satisfy the negative charge of the coordination entity [CoIII(L1)2]-. Electropolymerization of C1 produces a conductive metallopolymer deposit on fluorine-doped tin oxide (FTO) electrodes, which acts as an efficient glucose sensor, showing a linear amperometric response for glucose within a concentration range of 1.97 × 10 −7 M to 3.88 × 10−6 M (R2 = 0.993), limit of detection (LOD) of 9.27 × 10−7 M and limit of quantification (LOQ) of 9.24 × 10−6 M. This electrochemical sensor, which exhibit excellent reproducibility in the manufacturing process, was stable in environmental conditions and showed good reproducibility of the measurements for two weeks. In addition, the metallopolymer deposit was characterized by electrochemical techniques (cyclic voltammetry) and SEM microscopy.
AB - Through a simple and effective reaction of the cobalt (II) acetate tetrahydrate with a new ONO-tridentate Schiff base ligand (L1), which contains a thiophenyl group, a mono-anionic complex of formula: [{4-Th-C6H4-C(O)CH-C(CH3)=N-C6H4-2-O}2Co]-[Bu4N]+ (C1) was isolated. Spectroscopic tools (1H and 13C NMR, FT-IR) and the crystal structure revealed that C1 consists of a mononuclear six-coordinate anionic Co(III) center with a pseudo-octahedral geometry, and one tetrabutylammonium counterion to satisfy the negative charge of the coordination entity [CoIII(L1)2]-. Electropolymerization of C1 produces a conductive metallopolymer deposit on fluorine-doped tin oxide (FTO) electrodes, which acts as an efficient glucose sensor, showing a linear amperometric response for glucose within a concentration range of 1.97 × 10 −7 M to 3.88 × 10−6 M (R2 = 0.993), limit of detection (LOD) of 9.27 × 10−7 M and limit of quantification (LOQ) of 9.24 × 10−6 M. This electrochemical sensor, which exhibit excellent reproducibility in the manufacturing process, was stable in environmental conditions and showed good reproducibility of the measurements for two weeks. In addition, the metallopolymer deposit was characterized by electrochemical techniques (cyclic voltammetry) and SEM microscopy.
KW - Electrodeposition
KW - Glucose sensor
KW - Metallopolymer
KW - Schiff base cobaltate (III) complex
UR - http://www.scopus.com/inward/record.url?scp=85096911980&partnerID=8YFLogxK
U2 - 10.1016/j.synthmet.2020.116633
DO - 10.1016/j.synthmet.2020.116633
M3 - Article
AN - SCOPUS:85096911980
VL - 271
JO - Synthetic Metals
JF - Synthetic Metals
SN - 0379-6779
M1 - 116633
ER -