Antioxidant, phenolic and antifungal profiles of Acanthus mollis (Acanthaceae).

Carlos Jara, Miguel Leyton, Mauricio Osorio, Viviana Silva, Francisco Fleming, Marilyn Paz, Alejandro Madrid, Marco Mellado

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Acanthus mollis is used as ornamental and medicinal plant. The ethnopharmacology reports indicate that extracts have anti-inflammatory activity. Phytoconstituents profile was evaluated by estimating the content of anthraquinones, flavonoids and phenols. In addition, the antioxidant activity was evaluated using four methods: Hydrogen atoms transfer (TRAP, ORAC and DPPH assays), and single electron transfer (FRAP assay). Finally, antifungal activity was determined by the M27-A2 test. The results shown that ethanol extracts have the highest concentration of phenols, anthraquinones and flavonoids. Total antioxidant capacity, extracts of ethyl acetate and ethanol are those with the highest activity, which correlates strongly with the presence of phenols. The antifungal activity measured in various strains of Candida is concentrated in ethyl acetate extracts of flower and leaf ethanol, a phenomenon may be related to antioxidant activity.

Original languageEnglish
Pages (from-to)2325-2328
Number of pages4
JournalNatural Product Research
Volume31
Issue number19
DOIs
StatePublished - 2017
Externally publishedYes

Keywords

  • Acanthus mollis
  • antifungal activity
  • antioxidant activity
  • phenolic compounds

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