TY - JOUR
T1 - Antioxidant, phenolic and antifungal profiles of Acanthus mollis (Acanthaceae).
AU - Jara, Carlos
AU - Leyton, Miguel
AU - Osorio, Mauricio
AU - Silva, Viviana
AU - Fleming, Francisco
AU - Paz, Marilyn
AU - Madrid, Alejandro
AU - Mellado, Marco
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017
Y1 - 2017
N2 - Acanthus mollis is used as ornamental and medicinal plant. The ethnopharmacology reports indicate that extracts have anti-inflammatory activity. Phytoconstituents profile was evaluated by estimating the content of anthraquinones, flavonoids and phenols. In addition, the antioxidant activity was evaluated using four methods: Hydrogen atoms transfer (TRAP, ORAC and DPPH assays), and single electron transfer (FRAP assay). Finally, antifungal activity was determined by the M27-A2 test. The results shown that ethanol extracts have the highest concentration of phenols, anthraquinones and flavonoids. Total antioxidant capacity, extracts of ethyl acetate and ethanol are those with the highest activity, which correlates strongly with the presence of phenols. The antifungal activity measured in various strains of Candida is concentrated in ethyl acetate extracts of flower and leaf ethanol, a phenomenon may be related to antioxidant activity.
AB - Acanthus mollis is used as ornamental and medicinal plant. The ethnopharmacology reports indicate that extracts have anti-inflammatory activity. Phytoconstituents profile was evaluated by estimating the content of anthraquinones, flavonoids and phenols. In addition, the antioxidant activity was evaluated using four methods: Hydrogen atoms transfer (TRAP, ORAC and DPPH assays), and single electron transfer (FRAP assay). Finally, antifungal activity was determined by the M27-A2 test. The results shown that ethanol extracts have the highest concentration of phenols, anthraquinones and flavonoids. Total antioxidant capacity, extracts of ethyl acetate and ethanol are those with the highest activity, which correlates strongly with the presence of phenols. The antifungal activity measured in various strains of Candida is concentrated in ethyl acetate extracts of flower and leaf ethanol, a phenomenon may be related to antioxidant activity.
KW - Acanthus mollis
KW - antifungal activity
KW - antioxidant activity
KW - phenolic compounds
UR - http://www.scopus.com/inward/record.url?scp=85014633386&partnerID=8YFLogxK
U2 - 10.1080/14786419.2017.1299726
DO - 10.1080/14786419.2017.1299726
M3 - Article
C2 - 28274131
AN - SCOPUS:85014633386
SN - 1478-6419
VL - 31
SP - 2325
EP - 2328
JO - Natural Product Research
JF - Natural Product Research
IS - 19
ER -