Association models for binding of molecules to nanostructures

Manuel Ahumada, Eduardo Lissi, Ana Maria Montagut, FRANCISCO JAVIER VALENZUELA HENRIQUEZ, Natalia L. Pacioni, Emilio I. Alarcon

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

The interaction between nanoparticles and molecules plays a key role in determining the activity and performance of a given nanostructure. These interactions are pivotal for a variety of applications including drug delivery, surface manipulation for targeted therapies, and catalysis. However, to this day, gathering precise association parameters for the interaction of the molecules with nanostructures remains elusive and mostly imprecise. In this review, we present a critical discussion of the most commonly used techniques and models intended for determining the association of molecules with nanoparticles. Particular emphasis has been put on discussing the limitations and pitfalls related to determining association constants in this tutorial review.

Original languageEnglish
Pages (from-to)2067-2089
Number of pages23
JournalAnalyst
Volume142
Issue number12
DOIs
StatePublished - 21 Jun 2017
Externally publishedYes

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