TY - JOUR
T1 - Bacterial alginate production
T2 - an overview of its biosynthesis and potential industrial production
AU - Urtuvia, Viviana
AU - Maturana, Nataly
AU - Acevedo, Fernando
AU - Peña, Carlos
AU - Díaz-Barrera, Alvaro
N1 - Publisher Copyright:
© 2017, Springer Science+Business Media B.V.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Alginate is a linear polysaccharide that can be used for different applications in the food and pharmaceutical industries. These polysaccharides have a chemical structure composed of subunits of (1–4)-β-d-mannuronic acid (M) and its C-5 epimer α-l-guluronic acid (G). The monomer composition and molecular weight of alginates are known to have effects on their properties. Currently, these polysaccharides are commercially extracted from seaweed but can also be produced by Azotobacter vinelandii and Pseudomonas spp. as an extracellular polymer. One strategy to produce alginates with different molecular weights and with reproducible physicochemical characteristics is through the manipulation of the culture conditions during fermentation. This mini-review provides a comparative analysis of the metabolic pathways and molecular mechanisms involved in alginate polymerization from A. vinelandii and Pseudomonas spp. Different fermentation strategies used to produce alginates at a bioreactor laboratory scale are described.
AB - Alginate is a linear polysaccharide that can be used for different applications in the food and pharmaceutical industries. These polysaccharides have a chemical structure composed of subunits of (1–4)-β-d-mannuronic acid (M) and its C-5 epimer α-l-guluronic acid (G). The monomer composition and molecular weight of alginates are known to have effects on their properties. Currently, these polysaccharides are commercially extracted from seaweed but can also be produced by Azotobacter vinelandii and Pseudomonas spp. as an extracellular polymer. One strategy to produce alginates with different molecular weights and with reproducible physicochemical characteristics is through the manipulation of the culture conditions during fermentation. This mini-review provides a comparative analysis of the metabolic pathways and molecular mechanisms involved in alginate polymerization from A. vinelandii and Pseudomonas spp. Different fermentation strategies used to produce alginates at a bioreactor laboratory scale are described.
KW - Alginate
KW - Azotobacter vinelandii
KW - Pseudomonas spp
UR - http://www.scopus.com/inward/record.url?scp=85030854218&partnerID=8YFLogxK
U2 - 10.1007/s11274-017-2363-x
DO - 10.1007/s11274-017-2363-x
M3 - Review article
C2 - 28988302
AN - SCOPUS:85030854218
VL - 33
JO - World Journal of Microbiology & Biotechnology
JF - World Journal of Microbiology & Biotechnology
SN - 0959-3993
IS - 11
M1 - 198
ER -