Biochemical evidence associating membrane-encapsidated particles with reverse transcription in human gastric cancer.

SERGIO HERNAN MARSHALL GONZALEZ, G. E. Muñoz, G. Sierralta, A. Horvat

Research output: Contribution to journalArticlepeer-review

Abstract

We provide biochemical evidence demonstrating that membrane encapsidated structures present in terminal gastric patients share similar features with retrovirus-like particles. Purified particles reveal few polypeptides, one of them glycosylated. A ribonucleoprotein core-like component is recovered which retains the DNA-polymerizing activity and contains at least one RNA component which can be efficiently translated in vitro.

Original languageEnglish
Pages (from-to)835-839
Number of pages5
JournalCellular and molecular biology (Noisy-le-Grand, France)
Volume38
Issue number8
StatePublished - 1 Jan 1992

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