TY - JOUR
T1 - Communication between gastrointestinal bacteria and the nervous system
AU - Bravo, Javier A.
AU - Julio-Pieper, Marcela
AU - Forsythe, Paul
AU - Kunze, Wolfgang
AU - Dinan, Timothy G.
AU - Bienenstock, John
AU - Cryan, John F.
PY - 2012/12
Y1 - 2012/12
N2 - In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.
AB - In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.
UR - http://www.scopus.com/inward/record.url?scp=84870548338&partnerID=8YFLogxK
U2 - 10.1016/j.coph.2012.09.010
DO - 10.1016/j.coph.2012.09.010
M3 - Review article
C2 - 23041079
AN - SCOPUS:84870548338
SN - 1471-4892
VL - 12
SP - 667
EP - 672
JO - Current Opinion in Pharmacology
JF - Current Opinion in Pharmacology
IS - 6
ER -