Determination of organotin compounds by headspace solid-phase microextraction-gas chromatography-pulsed flame-photometric detection (HS-SPME-GC-PFPD)

Manuel Bravo, Gaëtane Lespes, Ida De Gregori, Hugo Pinochet, Martine Potin Gautier

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39 Scopus citations

Abstract

A method based on Headspace solid-phase microextraction (HS-SPME, with a 100 μm PDMS-fiber) in combination with gas-chromatography and pulsed flame-photometric detection (GC-PFPD) has been investigated for simultaneous determination of eight organotin compounds. Monobutyltin (MBT), dibutyltin (DBT), tributyltin (TBT), monophenyltin (MPhT), and the semi-volatile diphenyltin (DPhT), triphenyltin (TPhT), monooctyltin (MOcT), and dioctyltin (DOcT) were determined after derivatization with sodium tetraethylborate. The conditions used for the extraction and preconcentration step were optimised by experimental design methodology. Tripropyltin (TPrT) and diheptyltin (DHepT) were used as internal standards for quantification of volatile and semi-volatile organotin compounds, respectively. The analytical precision (RSD) for ten successive injections of a standard mixture containing all the organic tin compounds ranged between 2 and 11%. The limits of detection for all the organotin compounds were sub ng (Sn) L-1 in water and close to ng (Sn) kg-1 in sediments. The accuracy of the method was evaluated by analysis of two certified reference material (CRM) sediment samples. The HS-SPME-GC-PFPD was then applied to the analysis of three harbour sediment samples. The results showed that headspace SPME is an attractive tool for analysis of organotin compounds in solid environmental matrices.

Original languageEnglish
Pages (from-to)1082-1089
Number of pages8
JournalAnalytical and Bioanalytical Chemistry
Volume383
Issue number7-8
DOIs
StatePublished - Dec 2005

Keywords

  • Canonical analysis
  • Experimental design
  • Gas chromatography-pulsed flame photometric detection (GC-PFPD)
  • Organotin compounds
  • Solid-phase microextraction

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