Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model

Alexis A. Gonzalez; Emily L. Olsen; Stephanie Z. Killeen; Robert V. Blair; Surya V. Seshan; Edgar A. Jaimes; Chad J. Roy; Minolfa C. Prieto

doi:10.1111/jmp.12626

Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model

Alexis A. Gonzalez, Emily L. Olsen, Stephanie Z. Killeen, Robert V. Blair, Surya V. Seshan, Edgar A. Jaimes, Chad J. Roy, Minolfa C. Prieto

INSTITUTE OF CHEMISTRY

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19.

Original language	English
Pages (from-to)	131-134
Number of pages	4
Journal	Journal of Medical Primatology
Volume	52
Issue number	2
DOIs	https://doi.org/10.1111/jmp.12626
State	Published - Apr 2023

Keywords

African green monkey
SARS-CoV-2
acute kidney injury
nonhuman primate
renal injury

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10.1111/jmp.12626

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title = "Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model",

abstract = "Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19.",

keywords = "African green monkey, SARS-CoV-2, acute kidney injury, nonhuman primate, renal injury",

author = "Gonzalez, {Alexis A.} and Olsen, {Emily L.} and Killeen, {Stephanie Z.} and Blair, {Robert V.} and Seshan, {Surya V.} and Jaimes, {Edgar A.} and Roy, {Chad J.} and Prieto, {Minolfa C.}",

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AU - Gonzalez, Alexis A.

AU - Olsen, Emily L.

AU - Killeen, Stephanie Z.

AU - Blair, Robert V.

AU - Seshan, Surya V.

AU - Jaimes, Edgar A.

AU - Roy, Chad J.

AU - Prieto, Minolfa C.

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AB - Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19.

KW - African green monkey

KW - SARS-CoV-2

KW - acute kidney injury

KW - nonhuman primate

KW - renal injury

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JF - Journal of Medical Primatology

IS - 2

ER -

Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model

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