TY - JOUR
T1 - Front Microrheology of Biological Fluids
AU - Trejo-Soto, C. A.
AU - Costa-Miracle, E.
AU - Rodriguez-Villarreal, A. I.
AU - Cid, J.
AU - Castro, M.
AU - Alarcón, T.
AU - Hernández-Machado, A.
N1 - Funding Information:
C.T-S and A.H-M. gratefully acknowledge partial financialsupport from MINECO (Spain) under project FIS2013-47949-C01-01-P and AGAUR project 2014SGR-878. E.C-M, I.R-V, and T.A. gratefully acknowledge the spanish Ministry for Science and Innovation (MICINN) for funding under grants MTM2015-71509-C2-1-R and Generalitat de Catalunya for funding under grant 2014SGR1307. C.T-S acknowledges CONICYT and the Chilean Ministry of Education for funding PhD fellowship, Becas Chile.
Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2018/6/25
Y1 - 2018/6/25
N2 - We present a study of front microrheology through the development of a microfluidic device and method that describes accurately the non-linear rheology of blood, by means of a simple optical detection method based on tracking the fluid-air interface moving inside a microchannel. We study the behavior of Newtonian fluids of different viscosities and densities, as well, we performed measures for blood at different red blood cells concentration and at different days from its extraction. We have developed a scaling method which allows us to determine a relation between the red blood cell properties at different days from its extraction, according to the agreggation properties of red blood cell. Our results have been compared with theoretical and bibliographical results, which shows realiable results with an error around 6%. In general, our device and method is usefull as a viscometer and rheometer, as well as, it enables to establish a relation between blood viscosity and its red blood cells characteristics.
AB - We present a study of front microrheology through the development of a microfluidic device and method that describes accurately the non-linear rheology of blood, by means of a simple optical detection method based on tracking the fluid-air interface moving inside a microchannel. We study the behavior of Newtonian fluids of different viscosities and densities, as well, we performed measures for blood at different red blood cells concentration and at different days from its extraction. We have developed a scaling method which allows us to determine a relation between the red blood cell properties at different days from its extraction, according to the agreggation properties of red blood cell. Our results have been compared with theoretical and bibliographical results, which shows realiable results with an error around 6%. In general, our device and method is usefull as a viscometer and rheometer, as well as, it enables to establish a relation between blood viscosity and its red blood cells characteristics.
UR - http://www.scopus.com/inward/record.url?scp=85050126291&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1043/1/012058
DO - 10.1088/1742-6596/1043/1/012058
M3 - Conference article
AN - SCOPUS:85050126291
VL - 1043
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012058
Y2 - 30 November 2016 through 2 December 2016
ER -