Front Microrheology of Biological Fluids

CLAUDIA ANDREA TREJO SOTO, E. Costa-Miracle, A. I. Rodriguez-Villarreal, J. Cid, M. Castro, T. Alarcón, A. Hernández-Machado

Research output: Contribution to journalConference articlepeer-review

Abstract

We present a study of front microrheology through the development of a microfluidic device and method that describes accurately the non-linear rheology of blood, by means of a simple optical detection method based on tracking the fluid-air interface moving inside a microchannel. We study the behavior of Newtonian fluids of different viscosities and densities, as well, we performed measures for blood at different red blood cells concentration and at different days from its extraction. We have developed a scaling method which allows us to determine a relation between the red blood cell properties at different days from its extraction, according to the agreggation properties of red blood cell. Our results have been compared with theoretical and bibliographical results, which shows realiable results with an error around 6%. In general, our device and method is usefull as a viscometer and rheometer, as well as, it enables to establish a relation between blood viscosity and its red blood cells characteristics.

Original languageEnglish
Article number012058
JournalJournal of Physics: Conference Series
Volume1043
Issue number1
DOIs
StatePublished - 25 Jun 2018
Event20th Chilean Physics Symposium - Santiago, Chile
Duration: 30 Nov 20162 Dec 2016

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