NANoPoLC algorithm for correcting nanoparticle concentration by sample polydispersity

Caitlin Lazurko, Manuel Ahumada, Francisco Valenzuela-Henríquez, Emilio I. Alarcon

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Variability in the polydispersity of colloidal nanoparticles results in significant differences in the total number of nanoparticles available for the determination of their concentration, which ultimately affects their bioavailability and biodistribution. In the current work, we developed a novel algorithm, named Nanoparticle Polydispersity Corrector (NANoPoLC), which was shown to render a more realistic calculation of the actual nanoparticle concentration in solution.

Original languageEnglish
Pages (from-to)3166-3170
Number of pages5
JournalNanoscale
Volume10
Issue number7
DOIs
StatePublished - 21 Feb 2018
Externally publishedYes

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