NANoPoLC algorithm for correcting nanoparticle concentration by sample polydispersity

Caitlin Lazurko; Manuel Ahumada; Francisco Valenzuela-Henríquez; Emilio I. Alarcon

doi:10.1039/c7nr08672e

NANoPoLC algorithm for correcting nanoparticle concentration by sample polydispersity

Caitlin Lazurko, Manuel Ahumada, Francisco Valenzuela-Henríquez, Emilio I. Alarcon

INSTITUTE OF MATHEMATICS

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Variability in the polydispersity of colloidal nanoparticles results in significant differences in the total number of nanoparticles available for the determination of their concentration, which ultimately affects their bioavailability and biodistribution. In the current work, we developed a novel algorithm, named Nanoparticle Polydispersity Corrector (NANoPoLC), which was shown to render a more realistic calculation of the actual nanoparticle concentration in solution.

Original language	English
Pages (from-to)	3166-3170
Number of pages	5
Journal	Nanoscale
Volume	10
Issue number	7
DOIs	https://doi.org/10.1039/c7nr08672e
State	Published - 21 Feb 2018

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abstract = "Variability in the polydispersity of colloidal nanoparticles results in significant differences in the total number of nanoparticles available for the determination of their concentration, which ultimately affects their bioavailability and biodistribution. In the current work, we developed a novel algorithm, named Nanoparticle Polydispersity Corrector (NANoPoLC), which was shown to render a more realistic calculation of the actual nanoparticle concentration in solution.",

author = "Caitlin Lazurko and Manuel Ahumada and Francisco Valenzuela-Henr{\'i}quez and Alarcon, {Emilio I.}",

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AU - Ahumada, Manuel

AU - Valenzuela-Henríquez, Francisco

AU - Alarcon, Emilio I.

PY - 2018/2/21

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N2 - Variability in the polydispersity of colloidal nanoparticles results in significant differences in the total number of nanoparticles available for the determination of their concentration, which ultimately affects their bioavailability and biodistribution. In the current work, we developed a novel algorithm, named Nanoparticle Polydispersity Corrector (NANoPoLC), which was shown to render a more realistic calculation of the actual nanoparticle concentration in solution.

AB - Variability in the polydispersity of colloidal nanoparticles results in significant differences in the total number of nanoparticles available for the determination of their concentration, which ultimately affects their bioavailability and biodistribution. In the current work, we developed a novel algorithm, named Nanoparticle Polydispersity Corrector (NANoPoLC), which was shown to render a more realistic calculation of the actual nanoparticle concentration in solution.

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NANoPoLC algorithm for correcting nanoparticle concentration by sample polydispersity

Abstract

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