TY - JOUR
T1 - Not cat-scratch disease
T2 - Bartonella henselae neuroretinitis associated with non-feline pet mammals
AU - Orellana-Rios, Jorge
AU - Verdaguer-Diaz, Juan I.
AU - Opazo, Gabriela
AU - Leong, Belinda C.S.
AU - ZETT LOBOS, CLAUDIO MAURICIO
AU - Smith, R. Theodore
AU - Freund, K. Bailey
N1 - Funding Information:
R.T. Smith is supported in part by NIH/NEI Grant R01EY015520-10 .
Funding Information:
This work is also supported by The Macula Foundation Inc., New York, New York, USA .
Funding Information:
K. B. Freund is a consultant for Optovue, Heidelberg Engineering, Zeiss, Allergan, Bayer, Genentech, and Novartis and he receives research support from Genentech/Roche.R.T. Smith is supported in part by NIH/NEI Grant R01EY015520-10.This work is also supported by The Macula Foundation Inc., New York, New York, USA.
Publisher Copyright:
© 2020 The Authors
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/1
Y1 - 2020/1
N2 - To describe the ocurrence of Bartonella-associated neuroretinitis secondary to non-feline pet exposure, we retrospectively reviewed medical records and imaging from patients with a clinical and serologic diagnosis of Bartonella henselae (BH). Retinal imaging included color fundus photography, optical coherence tomography (OCT) and fluorescein angiography (FA). Four eyes of two patients with cat-scratch disease were included in this study, with a mean age of 35 years. The mean follow-up was 13 months, after presentation of infectious neuroretinitis. Both patients suffered from bilateral neuroretinitis after direct contact with family pets (ferret and guinea pig). All patients were treated with a long-term systemic antimicrobial therapy. Visual acuity in all improved to 20/30 or better at six months. In conclusion, humans may develop cat-scratch disease when they are exposed to Bartonella henselae (BH) in the saliva of infected cats or BH-containing flea feces reaching the systemic circulation through scratches or mucous membranes. As the cat flea (Ctenocephalides felis) may reside on non-feline mammals, Bartonella-associated neuroretinitis may result from contact with other furred family pets.
AB - To describe the ocurrence of Bartonella-associated neuroretinitis secondary to non-feline pet exposure, we retrospectively reviewed medical records and imaging from patients with a clinical and serologic diagnosis of Bartonella henselae (BH). Retinal imaging included color fundus photography, optical coherence tomography (OCT) and fluorescein angiography (FA). Four eyes of two patients with cat-scratch disease were included in this study, with a mean age of 35 years. The mean follow-up was 13 months, after presentation of infectious neuroretinitis. Both patients suffered from bilateral neuroretinitis after direct contact with family pets (ferret and guinea pig). All patients were treated with a long-term systemic antimicrobial therapy. Visual acuity in all improved to 20/30 or better at six months. In conclusion, humans may develop cat-scratch disease when they are exposed to Bartonella henselae (BH) in the saliva of infected cats or BH-containing flea feces reaching the systemic circulation through scratches or mucous membranes. As the cat flea (Ctenocephalides felis) may reside on non-feline mammals, Bartonella-associated neuroretinitis may result from contact with other furred family pets.
KW - Bartonella henselae
KW - Cat-scratch disease
KW - Ferret
KW - Guinea pig
KW - Neuroretinitis
KW - Retinitis
UR - http://www.scopus.com/inward/record.url?scp=85092325616&partnerID=8YFLogxK
U2 - 10.1016/j.idcr.2020.e00978
DO - 10.1016/j.idcr.2020.e00978
M3 - Article
AN - SCOPUS:85092325616
VL - 22
JO - IDCases
JF - IDCases
SN - 2214-2509
M1 - e00978
ER -
