Optical Coherence Tomography Angiography Findings in Diffuse Unilateral Subacute Neuroretinitis

Luiz H. Lima, Gustavo B. Melo, CLAUDIO MAURICIO ZETT LOBOS, Fábio B. Morais, Bruno C. Leal, Michel E. Farah, Rubens Belfort

Research output: Contribution to journalArticlepeer-review

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BACKGROUND AND OBJECTIVE: To report a unique case series of diffuse unilateral subacute neuroretinitis (DUSN) patients imaged with optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: In this retrospective case series, multimodal imaging was performed in four patients with DUSN at the time of patient visit. The study patients underwent standard clinical treatment for DUSN. RESULTS: The clinical findings were consistent with the diagnosis of DUSN. Cross-sectional OCT showed disruption of outer retinal layers in the foveal area and an irregular structure of the outer plexiform layer. En face OCT revealed hyperreflective spots and a large hyperreflective lesion in the foveal area correspondent to the outer retina disruption seen on cross-sectional OCT. OCTA demonstrated decreased vascular perfusion in both the superficial and deep retinal capillary plexuses along with choriocapillaris preservation. CONCLUSION: OCTA may provide a more detailed assessment of the retinal microvascular changes, allowing a more precise anatomical-functional correlation in DUSN.

Original languageEnglish
Pages (from-to)76-83
Number of pages8
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number2
StatePublished - Feb 2020
Externally publishedYes


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