Organometallic 1,5-benzodiazepine and 1,5-benzodiaze pinium compounds: Synthesis, characterization, X-ray diffraction structures and theoretical investigation

Cristina Gallardo, Alexander Trujillo, MAURICIO DANIEL FUENTEALBA CARRASCO, Andres Vega, David Carrillo, Carolina Manzur

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The organometallic tridentate ketoamine or enaminone compound, (η5-Cp)Fe(h5-CJH4)-C(=0)-CH= C(Me)-NH-C6H4-o-NH2, undergoes an intramolecular cyclocondensation promoted by Cu(C104) 2-6H20 (2:1 molar ratio) affording the neutral 2-ferrocenyl-4-methyl-1,5-benzodiazepine, 1. However, when the molar ratio used is 1:1, the ketoamine or enaminone compound transforms into the 2-ferrocenyl-4-methyl-1,5-benzodiazepinium cation, [2]+. The X-ray molecular structure of 1 exhibits a seven-membered ring with a boat conformation, and two folding dihedral angles along the N(l)-N(2) and C(11)-C(13) axes. In the case of [2]+, the structure shows only one folding dihedral angle along the N(l)-N(2) axis. A rationalization of the properties of 1 and [2]+ is provided through DFT calculations.

Original languageEnglish
Pages (from-to)1266-1270
Number of pages5
JournalJournal of the Chilean Chemical Society
Volume52
Issue number3
DOIs
StatePublished - 1 Jan 2007

Keywords

  • DFT calculations
  • Ferrocenyl enaminone
  • Ferrocenyl ketoamine
  • Organometallic diazepine
  • Organometallic diazepinium
  • X-ray structures

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