TY - JOUR
T1 - Speciation analysis of organotin compounds (OTCs) by a simultaneous hydride generation-liquid/liquid extraction and GC-MS determination
AU - Yáñez, Jorge
AU - Riffo, Paula
AU - Mansilla, Héctor D.
AU - Bravo, Manuel
AU - Quiroz, Waldo
AU - Santander, Paola
N1 - Funding Information:
The authors thank the support of the National Commission for Scientific and Technological Research (Conicyt) Fondecyt project nos. 1121128 , 1130502 and 1151296 , CONICYT/FONDAP/15110019 and CONICYT-PFB-0824 Center Optics and Photonics. Furthermore, the authors appreciate the support of Red Doctoral REDOC.CTA, MINEDUC project UCO1202 at the University of Concepción and the international collaboration program of Fondecyt project no. 1121128 for the financial support of Professor Dulasiri Amarasiriwardena visit to the Univerisity of Concepción.
Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - In the present work, the speciation analysis of three organotin compounds (OTCs), including tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT), by using simultaneous hydride generation-liquid/liquid extraction and GC-MS was developed. This simple method avoids the use of hazardous alkylation reagents without losing analytical performance. Multivariate design (central composite circumscribed, CCC) was applied for optimizing conditions on the hydride generation and liquid/liquid extraction. The optimized parameters were pH7.5 and NaBH4 concentration of 0.5% m/v. Hexane was the selected solvent for liquid extraction of OTC hydrides. Quantitative recoveries of OTCs were close to 100% in seawater samples, and the achieved detection limits for TBT, DBT, and MBT were 0.5, 0.4, and 0.7 μgL-1, respectively. Obtained analytical figures of merit were comparable or slight lower than the most used method using sodium tetraethylborate (NaBEt4) derivatization and GC-MS. Nevertheless, the proposed method is characterized by its simplicity, low cost, and the used of highly available and safe reagents and could be considered as an alternative to the established procedure in those labs where NaBEt4 is not available due the restriction to its transport or safety requirements.
AB - In the present work, the speciation analysis of three organotin compounds (OTCs), including tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT), by using simultaneous hydride generation-liquid/liquid extraction and GC-MS was developed. This simple method avoids the use of hazardous alkylation reagents without losing analytical performance. Multivariate design (central composite circumscribed, CCC) was applied for optimizing conditions on the hydride generation and liquid/liquid extraction. The optimized parameters were pH7.5 and NaBH4 concentration of 0.5% m/v. Hexane was the selected solvent for liquid extraction of OTC hydrides. Quantitative recoveries of OTCs were close to 100% in seawater samples, and the achieved detection limits for TBT, DBT, and MBT were 0.5, 0.4, and 0.7 μgL-1, respectively. Obtained analytical figures of merit were comparable or slight lower than the most used method using sodium tetraethylborate (NaBEt4) derivatization and GC-MS. Nevertheless, the proposed method is characterized by its simplicity, low cost, and the used of highly available and safe reagents and could be considered as an alternative to the established procedure in those labs where NaBEt4 is not available due the restriction to its transport or safety requirements.
KW - Borohydride
KW - Derivatization
KW - GC-MS
KW - Online liquid-liquid extraction
KW - TBT
KW - Tributyltin
UR - http://www.scopus.com/inward/record.url?scp=84954544163&partnerID=8YFLogxK
U2 - 10.1016/j.microc.2016.01.002
DO - 10.1016/j.microc.2016.01.002
M3 - Article
AN - SCOPUS:84954544163
VL - 126
SP - 460
EP - 465
JO - Microchemical Journal
JF - Microchemical Journal
SN - 0026-265X
ER -