TY - JOUR
T1 - Synthesis, characterization, and crystal structure of 2′,2″-dihydroxy-3,3⌄-bichalcone and its related chalcone-flavanone and biflavanone analogs
AU - Escobar, Carlos A.
AU - Fernández, Williams A.
AU - Trujillo, Alexander
AU - Santos, Juan C.
AU - Roisnel, Thierry
AU - FUENTEALBA CARRASCO, MAURICIO DANIEL
PY - 2014/9/17
Y1 - 2014/9/17
N2 - The synthesis of 3,3′-diformyl-1,1′-biphenyl 1 and its reaction in basic media with 2′-hydroxyacetophenone and paeonol, respectively, are described. The products, a bichalcone 2, it's partially cyclized analog, a flavanone-chalcone 3 and the fully cyclized biflavanone 4, are reported as products for the first reaction, while only the chalcone 5 for the second. The crystalline and molecular structure, solved by X-ray diffraction analysis, for compounds 2 and 5 are also presented in this work.
AB - The synthesis of 3,3′-diformyl-1,1′-biphenyl 1 and its reaction in basic media with 2′-hydroxyacetophenone and paeonol, respectively, are described. The products, a bichalcone 2, it's partially cyclized analog, a flavanone-chalcone 3 and the fully cyclized biflavanone 4, are reported as products for the first reaction, while only the chalcone 5 for the second. The crystalline and molecular structure, solved by X-ray diffraction analysis, for compounds 2 and 5 are also presented in this work.
KW - Bichalcone
KW - Biflavanone
KW - Biphenyl
KW - Chalcone
KW - Flavanone-chalcone
UR - http://www.scopus.com/inward/record.url?scp=84906957600&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2014.07.111
DO - 10.1016/j.tetlet.2014.07.111
M3 - Article
AN - SCOPUS:84906957600
VL - 55
SP - 5271
EP - 5274
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 38
ER -