Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives

Marcos Lorca, David Cabezas, Ileana Araque, Andrés Terán, Santiago Hernández, Marco Mellado, Luis Espinoza, Jaime Mella

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

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Resumen

Brassinosteroids are plant hormones whose main function is to stimulate plant growth. However, they have been studied for their biological applications in humans. Brassinosteroid compounds have displayed an important role in the study of cancer pathology and show potential for developing novel anticancer drugs. In this review we describe the relationship of brassinosteroids with cancer with focus on the last decade, the mechanisms of cytotoxic activity described to date, and a structure–activity relationship based on the available information.

Idioma originalInglés
Número de artículo109153
PublicaciónSteroids
Volumen190
DOI
EstadoPublicada - feb. 2023
Publicado de forma externa

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