Effect of temperature downshift on the transcriptomic responses of Chinese hamster ovary cells using recombinant human tissue plasminogen activator production culture

Agricultura y biología

• t-plasminogen activator 100%
• Chinese hamsters 72%
• transcriptomics 60%
• temperature 27%
• cells 21%
• cell culture 15%
• biopharmaceuticals 12%
• biogenesis 10%
• glycosylation 9%
• DNA damage 9%
• recombinant proteins 9%
• energy metabolism 9%
• cell death 9%
• cell viability 9%
• cell proliferation 8%
• cell growth 8%
• mitochondria 7%
• developmental stages 6%
• genes 6%
• metabolism 5%
• proteins 3%

Medicina y ciencias biológicas

• Tissue Plasminogen Activator 73%
• Cricetulus 73%
• Ovary 60%
• Temperature 49%
• High-Throughput Nucleotide Sequencing 18%
• Cell Culture Techniques 14%
• Organelle Biogenesis 12%
• Glycosylation 10%
• Growth 9%
• Biological Products 9%
• Recombinant Proteins 9%
• Energy Metabolism 8%
• DNA Damage 8%
• Mitochondria 8%
• Genes 7%
• Cell Survival 7%
• Cell Death 7%
• Cell Proliferation 6%
• Proteins 3%

Química

• Pharmacological Metabolism 53%
• Process Dynamics 40%
• Apoptotic 39%
• Cell Death 36%
• Mammalian Cell 35%
• Glycosylation 34%
• Cell Viability 34%
• Protein 28%
• Energy 16%