Gut Susceptibility to Viral Invasion: Contributing Roles of Diet, Microbiota and Enteric Nervous System to Mucosal Barrier Preservation

MARCELA JULIO PIEPER, Alejandra López-Aguilera, Johana Eyzaguirre-Velásquez, Loreto Olavarría-Ramírez, Claudia Ibacache-Quiroga, JAVIER ANDRES BRAVO VIVALLO, Gonzalo Cruz

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3 Citas (Scopus)

Resumen

The gastrointestinal lumen is a rich source of eukaryotic and prokaryotic viruses which, together with bacteria, fungi and other microorganisms comprise the gut microbiota. Pathogenic viruses inhabiting this niche have the potential to induce local as well as systemic complications; among them, the viral ability to disrupt the mucosal barrier is one mechanism associated with the promotion of diarrhea and tissue invasion. This review gathers recent evidence showing the contributing effects of diet, gut microbiota and the enteric nervous system to either support or impair the mucosal barrier in the context of viral attack.

Idioma originalInglés
PublicaciónInternational Journal of Molecular Sciences
Volumen22
N.º9
DOI
EstadoPublicada - 29 abr. 2021
Publicado de forma externa

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