TY - CHAP
T1 - Technical and economic analysis of industrial production of lactose-derived prebiotics with focus on galacto-oligosaccharides
AU - Scott, Felipe
AU - Vera, Carlos
AU - Conejeros, Raúl
N1 - Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.
PY - 2016/7/7
Y1 - 2016/7/7
N2 - Galactooligosaccharides (GOS) are the most relevant prebiotics synthesized from lactose. During the last decades, a number of processes have been reported for its industrial production using β-galactosidase as catalyst. However, economic and technical analyses are seldom published. This chapter analyzes a number of processes for GOS production considering two sources of β-galactosidase and several purification strategies from a technical and economic point of view. Among the purification alternatives, simulated moving bed chromatography and removal of unwanted mono and disaccharides by bioconversion with yeast are included. Process alternatives are compared within a common price framework using the minimum product selling price. Results show that the calculated minimum selling prices are well below the market prices for GOS, thus leaving room for marketing and distribution costs. Furthermore, the integration of GOS production to an existing dairy industry is analyzed focusing in plant capacity, installed equipment and market lactose and whey prices.
AB - Galactooligosaccharides (GOS) are the most relevant prebiotics synthesized from lactose. During the last decades, a number of processes have been reported for its industrial production using β-galactosidase as catalyst. However, economic and technical analyses are seldom published. This chapter analyzes a number of processes for GOS production considering two sources of β-galactosidase and several purification strategies from a technical and economic point of view. Among the purification alternatives, simulated moving bed chromatography and removal of unwanted mono and disaccharides by bioconversion with yeast are included. Process alternatives are compared within a common price framework using the minimum product selling price. Results show that the calculated minimum selling prices are well below the market prices for GOS, thus leaving room for marketing and distribution costs. Furthermore, the integration of GOS production to an existing dairy industry is analyzed focusing in plant capacity, installed equipment and market lactose and whey prices.
KW - Investment costs
KW - Operational costs
KW - Prebiotics minimum selling price
KW - Prebiotics techno-economic analysis
KW - Selective fermentations
KW - Simulated moving bed chromatography
UR - http://www.scopus.com/inward/record.url?scp=84987788959&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-802724-0.00007-X
DO - 10.1016/B978-0-12-802724-0.00007-X
M3 - Chapter
AN - SCOPUS:84987788959
SN - 9780128027240
SP - 261
EP - 284
BT - Lactose-Derived Prebiotics
PB - Elsevier Inc.
ER -